Rostral ventral medulla cholinergic mechanism in pain-induced analgesia

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Permanent lesion in rostral ventromedial medulla potentiates swim stress-induced analgesia in formalin test

Objective(s): There are many reports about the role of rostral ventromedial medulla (RVM) in modulating stress-induced analgesia (SIA). In the previous study we demonstrated that temporal inactivation of RVM by lidocaine potentiated stress-induced analgesia. In this study, we investigated the effect of permanent lesion of the RVM on SIA by using formalin test as a model of acute inflammatory pa...

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permanent lesion in rostral ventromedial medulla potentiates swim stress-induced analgesia in formalin test

objective(s): there are many reports about the role of rostral ventromedial medulla (rvm) in modulating stress-induced analgesia (sia). in the previous study we demonstrated that temporal inactivation of rvm by lidocaine potentiated stress-induced analgesia. in this study, we investigated the effect of permanent lesion of the rvm on sia by using formalin test as a model of acute inflammatory pa...

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Effect of transient inactivation of rostral ventromedial medulla on swim stress induced analgesia in formalin test in rats

Introduction: Despite significant progress in understanding pain control mechanism, there are numerous questions about central nervous mechanisms underlying stress-induced analgesia. The rostral ventromedial medulla (RVM) in the brainstem integrates a variety of functions, including pain modulation and pain perception. In the present study, we investigated the effect of temporary inactivatio...

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Permanent lesion in rostral ventromedial medulla potentiates swim stress-induced analgesia in formalin test

OBJECTIVE(S) There are many reports about the role of rostral ventromedial medulla (RVM) in modulating stress-induced analgesia (SIA). In the previous study we demonstrated that temporal inactivation of RVM by lidocaine potentiated stress-induced analgesia. In this study, we investigated the effect of permanent lesion of the RVM on SIA by using formalin test as a model of acute inflammatory pai...

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Repetitive Electroacupuncture Attenuates Cold-Induced Hypertension through Enkephalin in the Rostral Ventral Lateral Medulla

Acupuncture lowers blood pressure (BP) in hypertension, but mechanisms underlying its action are unclear. To simulate clinical studies, we performed electroacupuncture (EA) in unanesthetized rats with cold-induced hypertension (CIH) induced by six weeks of cold exposure (6 °C). EA (0.1 - 0.4 mA, 2 Hz) was applied at ST36-37 acupoints overlying the deep peroneal nerve for 30 min twice weekly for...

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ژورنال

عنوان ژورنال: Neuroscience Letters

سال: 2009

ISSN: 0304-3940

DOI: 10.1016/j.neulet.2009.08.036